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Conversely, while certain trials exploring CB-839 alone or in combination with other therapies have exhibited less auspicious results, the potential value of CB-839 as a complementary component to existing treatment paradigms persists [218]

Jez Frontiers in Plant Science doi 10.3389/fpls.2011.00045 19,164 views 106 citations Original Research Published on 03 Dec 2021 Suppression of the Lycopene Cyclase Gene Causes Downregulation of Ascorbate Peroxidase Activity and Decreased Glutathione Pool Size, Leading to H2O2 Accumulation in Euglena gracilis in Aquatic Photosynthetic Organisms Shun Tamaki Ryosuke Sato Yuki Koshitsuka Masashi Asahina Yutaka Kodama Takahiro Ishikawa Tomoko Shinomura Frontiers in Plant Science doi 10.3389/fpls.2021.786208 5,380 views 9 citations Original Research Published on 03 Dec 2025 Effect of end-of-production light treatment under different light/dark alternating frequencies on ascorbic acid accumulation and metabolism of hydroponic lettuce in Plant Physiology Dong Yu Zonggeng Li Jiangtao Hu Fang Wang Wei Lu Quan Yuan Sen Wang Chengbo Zhou Qichang Yang Frontiers in Plant Science doi 10.3389/fpls.2025.1681893 1,791 views

Acyltransferases mediating butyrylation exhibited distinct substrate specificities: in vitro studies demonstrated that CBP/p300 (CREB-binding protein/E1A binding protein p300) directly butyrylates both histone H4 and non-histone protein p53 [58], whereas Gcn5 mutation significantly reduced histone H3 butyrylation [60]